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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

XVI.ab Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

1
Last update : 30/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Asymptomatic cavitary pneumonitis due to amiodarone pulmonary toxicity.
Texas Heart Institute journal 1985 Dec;12;371-5 1985 Dec
Acute necrotizing pneumonitis and hyperglycemia after amiodarone therapy. Case report and review of amiodarone-associated pulmonary disease.
The American journal of medicine 1984 May;76;935-9 1984 May

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