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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

2
Last update : 11/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Organizing pneumonia secondary to amiodarone treatment.
Heliyon 2022 Sep;8;e10630 2022 Sep
Cryptogenic and secondary organizing pneumonia: clinical presentation, radiographic findings, treatment response, and prognosis.
Chest 2011 Apr;139;893-900 2011 Apr
[Bronchiolitis obliterans with organized pneumonia secondary to amiodarone: presentation of two cases with different therapeutic approach].
Revista clinica espanola 2009 Dec;209;568-9 2009 Dec
Organizing pneumonia: typical and atypical HRCT patterns.
La Radiologia medica 2006 Mar;111;202-12 2006 Mar
Bronchiolitis obliterans organizing pneumonia. Clinical and roentgenological features in 26 cases.
Respiration; international review of thoracic diseases 2005;72;254-62 2005
Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage.
Archives of pathology & laboratory medicine 2002 Sep;126;1064-70 2002 Sep
Bronchiolitis obliterans organising pneumonia secondary to amiodarone treatment.
The Netherlands journal of medicine 1998 Sep;53;109-12 1998 Sep
Bronchiolitis obliterans organizing pneumonia during low-dose amiodarone therapy.
Clinical cardiology 1997 Mar;20;300-2 1997 Mar
Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: clinical, radiological and histological pattern.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 1997 Feb;52;24-6 1997 Feb
Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: a rare aetiology.
The European respiratory journal 1995 Mar;8;470-1 1995 Mar
Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone.
Thorax 1989 Sep;44;711-5 1989 Sep
Amiodarone pneumonitis: three further cases with a review of published reports.
Thorax 1984 Jan;39;57-64 1984 Jan

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