Pneumotox » Drug » Amiodarone » XVIII.k - Eye-catcher: An electron-dense liver on unenhanced CT

Amiodarone

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XVIII.k Eye-catcher: An electron-dense liver on unenhanced CT

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Last update : 31/08/2013

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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