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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amiodarone

5

X.d Lupus - Lupus syndrome (see also Vd)

2
Last update : 05/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dronedarone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Thyroid hormones (exogenous)
1

Publications

Amiodarone-induced lupus-like syndrome.
American journal of therapeutics 2015;22;e20-1 2015
An unexpected side-effect of a commonly used drug.
Boletin de la Asociacion Medica de Puerto Rico 2013;105;50-2 2013
Amiodarone-induced systemic lupus erythematosus.
The Journal of the Association of Physicians of India 2003 Feb;51;216-7 2003 Feb

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