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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Apalutamide
1
I.f
Acute fibrinous organizing pneumonia (AFOP)
1
Last update :
15/03/2025
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Androgen deprivation therapy (Antiandrogens)
Bicalutamide
Nilutamide
Publications
A challenging case of drug-related acute fibrinous and organizing pneumonia: A rare case report.