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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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COVID19 (SARS-CoV2) vaccination/vaccine

5

X.be A flare of preexisting immune-mediated systemic/rheumatic disease

1
Last update : 23/07/2021
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Immune-Mediated Disease Flares or New-Onset Disease in 27 Subjects Following mRNA/DNA SARS-CoV-2 Vaccination.
Vaccines 2021 Apr 29;9; 2021 Apr 29

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