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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Naltrexone

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 03/11/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

From Medication to Complication: A Case Report of Acute Eosinophilic Pneumonia Associated With Naltrexone.
Clinical case reports 2025 Apr;13;e70372 2025 Apr
A case of naltrexone-induced acute eosinophilic pneumonia.
BMJ case reports 2024 May 02;17; 2024 May 02
A Case for Biopsy: Injectable Naltrexone-Induced Acute Eosinophilic Pneumonia.
Cureus 2020 Sep 03;12;e10221 2020 Sep 03

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