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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lorcaserin

1

XII.b Valvular heart disease and/or dysfunction

1
Last update : 22/03/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

The cardiovascular safety of antiobesity drugs-analysis of signals in the FDA Adverse Event Report System Database.
International journal of obesity (2005) 2020 May;44;1021-1027 2020 May

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