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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiocontrast media (RCM)

5

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 02/04/2022
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Gadobutrol
2
Gadolinium-based MRI contrast media
2
Iodixanol
1
Iohexol
1

Publications

Fatal noncardiogenic pulmonary edema related to nonionic, iso-osmolar iodine contrast medium: one case report.
BMC pulmonary medicine 2022 Mar 31;22;118 2022 Mar 31
Acute pulmonary edema induced by non-ionic low-osmolar radiographic contrast media.
Open access emergency medicine : OAEM 2018;10;75-79 2018
[Pulmonary oedema subsequent to radiographic contrast in a computed tomography of the coronary arteries].
Ugeskrift for laeger 2012 May 07;174;1316-7 2012 May 07
Case reports of death after nonionic iodine contrast medium injection during spiral computed tomography scan performed for suspected pulmonary embolism.
The American journal of emergency medicine 2006 Jul;24;497-9 2006 Jul
Review article: Effects of radiographic contrast media on the lung.
The British journal of radiology 2003 May;76;290-5 2003 May
Fatal non-cardiogenic pulmonary oedema after intravenous non-ionic radiographic contrast.
Lancet (London, England) 2002 Mar 23;359;1037-8 2002 Mar 23
Pulmonary edema following intravenous injection of nonionic low-osmolar contrast medium--appearance on HRCT. A case report.
Acta radiologica (Stockholm, Sweden : 1987) 1998 Jan;39;81-3 1998 Jan
Non-cardiogenic pulmonary oedema after intravenous administration of non-ionic contrast media.
Acta radiologica (Stockholm, Sweden : 1987) 1996 Sep;37;823-5 1996 Sep
Noncardiogenic pulmonary edema induced by nonionic low-osmolality radiographic contrast media.
The Journal of allergy and clinical immunology 1995 Nov;96;698-9 1995 Nov
Noncardiogenic pulmonary edema associated with intravenous radiocontrast administration.
Chest 1992 Aug;102;620-1 1992 Aug
Noncardiogenic pulmonary edema resulting from intravascular administration of contrast material.
AJR. American journal of roentgenology 1991 Aug;157;255-6 1991 Aug
Radiographic contrast media-induced noncardiogenic pulmonary edema: case report and review of the literature.
The Journal of allergy and clinical immunology 1984 Jul;74;104-7 1984 Jul
Non-cardiogenic pulmonary edema following intravenous pyelography.
Connecticut medicine 1982 Apr;46;180-2 1982 Apr
Shock lung with massive tracheal loss of plasma.
JAMA 1977 Jun 06;237;2511-3 1977 Jun 06
Retinal embolism after hysterosalpingography.
The British journal of ophthalmology 1973 Mar;57;166-9 1973 Mar

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