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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiocontrast media (RCM)

5

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Gadobutrol
2
Gadolinium-based MRI contrast media
2
Iodixanol
1
Iohexol
1

Publications

Chronic eosinophilic pneumonia due to radiographic contrast administration: an orphan disease?
Drug design, development and therapy 2012;6;385-9 2012
Peripheral blood eosinophilia associated with gastrointestinal administration of iodinated contrast media.
AJR. American journal of roentgenology 2003 Mar;180;751-3 2003 Mar
Löffler's Syndrome as a complication of bipedal lymphangiography.
JAMA 1970 Oct 12;214;369-71 1970 Oct 12

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