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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Interleukin 2 (IL2)

3

XII.a Left or biventricular dysfunction/failure

1
Last update : 15/08/2022
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Acute and Chronic Cardiopulmonary Effects of High Dose Interleukin-2 Therapy: An Observational Magnetic Resonance Imaging Study.
Diagnostics (Basel, Switzerland) 2022 May 30;12; 2022 May 30

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