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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dupilumab

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 07/08/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A case of recurrent chronic eosinophilic pneumonia after switching from benralizumab to dupilumab.
Respiratory medicine case reports 2024;47;101968 2024
Eosinophilic pneumonia developed after dupilumab administration in a patient with atopic dermatitis.
Respirology case reports 2023 Aug;11;e01192 2023 Aug
A case of chronic eosinophilic pneumonia in a patient treated with dupilumab.
Therapeutics and clinical risk management 2019;15;869-875 2019

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