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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Indigo

1

VI.b Pulmonary arterial hypertension

1
Last update : 24/05/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dyes
3

Publications

Adverse events in patients with ulcerative colitis treated with indigo naturalis: a Japanese nationwide survey.
Journal of gastroenterology 2019 Oct;54;891-896 2019 Oct
Chinese herbal drug natural indigo may cause pulmonary artery hypertension.
European heart journal 2016 Jul 01;37;1992 2016 Jul 01

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