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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Infliximab

5

XVII.b Opportunistic pulmonary/systemic infections

3
Last update : 30/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Biosimilars
1
Infliximab biosimilar
1
TNF-alpha antagonists / inhibitors
5

Publications

Disseminated Nocardiosis Associated with Treatment with Infliximab in a Patient with Ulcerative Colitis.
The American journal of case reports 2017 Dec 21;18;1365-1369 2017 Dec 21
Mycobacterial diseases and antitumour necrosis factor therapy in USA.
Annals of the rheumatic diseases 2013 Jan;72;37-42 2013 Jan
Pneumocystis jirovecii colonization in patients treated with infliximab.
European journal of clinical investigation 2011 Mar;41;343-8 2011 Mar
Drug-specific risk of non-tuberculosis opportunistic infections in patients receiving anti-TNF therapy reported to the 3-year prospective French RATIO registry.
Annals of the rheumatic diseases 2011 Apr;70;616-23 2011 Apr
Cough and fever in a female with Crohn's disease receiving infliximab.
The European respiratory journal 2005 Aug;26;354-7 2005 Aug
Cavitating pneumonia after treatment with infliximab and prednisone.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2004 Aug;23;638-41 2004 Aug
Pulmonary cryptococcosis after initiation of anti-tumor necrosis factor-alpha therapy.
Chest 2003 Dec;124;2395-7 2003 Dec

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