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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Infliximab

5

XVII.c Aspergillosis, pulmonary (invasive, allergic [ABPA], or mycetoma)

1
Last update : 26/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Biosimilars
1
Infliximab biosimilar
1
TNF-alpha antagonists / inhibitors
5

Publications

Development of Allergic Bronchopulmonary Aspergillosis in a Patient with Crohn's Disease.
Internal medicine (Tokyo, Japan) 2019 Oct 01;58;2835-2838 2019 Oct 01
A case of fatal invasive aspergillosis in a patient with neurosarcoidosis treated with infliximab.
The International journal of neuroscience 2019 Jun;129;619-622 2019 Jun
Allergic bronchopulmonary aspergillosis after infliximab therapy for sarcoidosis: a potential mechanism related to T-helper cytokine balance.
Chest 2009 May;135;1358-1359 2009 May
Invasive pulmonary aspergillosis soon after therapy with infliximab, a tumor necrosis factor-alpha-neutralizing antibody: a possible healthcare-associated case?
Infection control and hospital epidemiology 2003 Jul;24;477-82 2003 Jul

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