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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Household/cleansing agents

5

IV.c Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

1
Last update : 17/02/2021
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Chemicals
5
Gases
5
Gasoline (inhaled, i.v.)
1
Oil-/lipid-based formulations (parenteral)
3
Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated
5
Waterpipe (narghile, shisha) smoking
5
Waterproofing agents/sprays - Household cleansing agents and aerosols
5

Publications

Severe airway disease due to inhalation of fumes from cleansing agents.
Chest 1976 Mar;69;372-6 1976 Mar

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