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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Imipramine

2

II.b ARDS - Acute lung injury

1
Last update : 14/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Adult respiratory distress syndrome and late death following imipramine overdose: a case report.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 1994 Dec;54;436-41 1994 Dec
ARDS associated with massive imipramine overdose.
The American journal of emergency medicine 1986 Mar;4;195-7 1986 Mar

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