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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
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Food - Food products - Food additives
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Severe or catastrophic bronchospasm or asthma attack (can be fatal)
1
Last update :
02/06/2019
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Antifreeze
Cyanide
Herbals - Dietary botanical therapy - Health products/food - Plants
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Clustered Outbreak of Adverse Reactions to a Salsa Containing High Levels of Sulfites.