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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydrocortisone

2

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 05/09/2013
 
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Corticosteroids, systemic (oral, parenteral)
5

Publications

Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics.
The Journal of allergy and clinical immunology 1981 Sep;68;201-4 1981 Sep
Adverse bronchial reactions to intravenous hydrocortisone in two aspirin-sensitive asthmatic patients.
British medical journal 1978 Jun 10;1;1521-2 1978 Jun 10

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