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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydrochlorothiazide

3

XII.n Cardiovascular collapse - Cardiogenic shock - Hypotension

1
Last update : 07/01/2014
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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Publications

Hydrochlorothiazide-induced systemic capillary leak.
The American journal of emergency medicine 2020 Jun;38;1299.e1-1299.e2 2020 Jun
Severe allergic reaction to hydrochlorothiazide mimicking septic shock.
Pharmacotherapy 2009 Mar;29;357-61 2009 Mar
Hydrochlorothiazide-associated noncardiogenic pulmonary oedema and shock: a case report and review of the literature.
Acta cardiologica 2007 Apr;62;215-20 2007 Apr
Pulmonary oedema with shock induced by hydrochlorothiazide: a rare side effect mimicking myocardial infarction.
British heart journal 1990 Mar;63;186 1990 Mar
[Hydrochlorothiazide-induced lung edema with shock].
Schweizerische medizinische Wochenschrift 1988 Jan 31;118;139-42 1988 Jan 31

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