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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydrochlorothiazide

3

II.b ARDS - Acute lung injury

2
Last update : 21/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Recurrent Hydrochlorothiazide-Induced Acute Respiratory Distress Syndrome Treated With Extracorporeal Membrane Oxygenation.
The Journal of emergency medicine 2018 Dec;55;836-840 2018 Dec
Acute allergic interstitial pneumonitis induced by hydrochlorothiazide.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 1991 Jul 01;145;28-34 1991 Jul 01

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