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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ranimustine

1

II.b ARDS - Acute lung injury

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Last update : 09/09/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Nitrosoureas (suffixes '-NU', '-mustine')
4

Publications

Safety and efficacy of high-dose ranimustine (MCNU) containing regimen followed by autologous stem cell transplantation for diffuse large B-cell lymphoma.
International journal of hematology 2018 Nov;108;510-515 2018 Nov

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