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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Heroin (intravenous)
5
IV.a
Bronchospasm - Wheezing - Asthma
3
Last update :
10/08/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
Heroin (inhaled, insufflated, snorted)
Methadone
Opiates - Opioids - Opium
Publications
Heroin insufflation as a trigger for patients with life-threatening asthma.
Inhaled heroin-induced status asthmaticus: five cases and a review of the literature.
[Heroin inhalation-induced asthma and eosinophilic pneumonia].
Asthma in opiate addicts.