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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Heroin (intravenous)

5

XI.r Death following exposure or poisoning

5
Last update : 04/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Heroin (inhaled, insufflated, snorted)
4
Methadone
5
Opiates - Opioids - Opium
5

Publications

Post-mortem whole body computed tomography of opioid (heroin and methadone) fatalities: frequent findings and comparison to autopsy.
European radiology 2014 Jun;24;1276-82 2014 Jun
Heroin body packer's death in Haryana; India: a case report.
Journal of forensic and legal medicine 2013 Aug;20;693-6 2013 Aug
The histopathology of drugs of abuse.
Histopathology 2011 Oct;59;579-93 2011 Oct
The comparative toxicology and major organ pathology of fatal methadone and heroin toxicity cases.
Drug and alcohol dependence 2010 Jan 01;106;1-6 2010 Jan 01
Outcome of acute heroin overdose requiring intensive care unit admission.
Journal of opioid management 2010;6;227-31 2010
A clinical study of an epidemic of heroin intoxication and heroin-induced pulmonary edema.
The American journal of medicine 1971 Dec;51;704-14 1971 Dec

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