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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Heparin

4

V.n Hemopericardium - Bloody pericardial effusion

1
Last update : 11/08/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Heparin, low-m.w.
1

Publications

Heparin-induced cardiac tamponade and life-threatening hyperkalema in a patient with chronic hemodialysis.
The Kaohsiung journal of medical sciences 2005 Mar;21;128-33 2005 Mar
Cardiac tamponade secondary to hemorrhagic pericarditis during continuous hemofiltration for renal failure. The role of the anticoagulant.
Renal failure 1994;16;299-301 1994
Fatal cardiac tamponade in systemic lupus erythematosus--a hazard of anticoagulation.
American heart journal 1990 Feb;119;422-3 1990 Feb

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