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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Heparin

4

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 28/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Heparin, low-m.w.
1

Publications

Allergic anaphylaxis due to subcutaneously injected heparin.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2013 Jan 10;9;1 2013 Jan 10

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