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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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P2Y12 antiplatelet therapy

2

XII.s Heart block (bundle branch- or AV-)

1
Last update : 04/11/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ticagrelor
5

Publications

Changes in Treatment Patterns and Incremental Health Care Utilization Due to P2Y12-Associated Complications in Patients with Acute Coronary Syndrome.
Journal of managed care & specialty pharmacy 2017 Sep;23;947-956 2017 Sep

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