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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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G/GM-CSF

3

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1
Last update : 16/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary micro-embolism in a healthy donor following G-CSF administration for mobilization of hemopoietic progenitor cells.
Bone marrow transplantation 2012 Feb;47;308-10 2012 Feb

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