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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Abiraterone

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 01/09/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A Phase I Study of Abiraterone Acetate Combined with BEZ235, a Dual PI3K/mTOR Inhibitor, in Metastatic Castration Resistant Prostate Cancer.
The oncologist 2017 May;22;503-e43 2017 May

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