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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adrenocorticotropic hormone (ACTH)

2

XVII.e Pneumocystis jiroveci pneumonia

1
Last update : 17/02/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Corticosteroids, systemic (oral, parenteral)
5

Publications

[Severe infection by Pneumocystis jirovecii in infants with West's syndrome treated with intramuscular adrenocorticotropic hormone].
Revista de neurologia 2016 Jan 16;62;92-5 2016 Jan 16
Pneumocystis carinii pneumonia in a child receiving ACTH for infantile spasms.
Pediatric pulmonology 1999 Apr;27;286-9 1999 Apr
Pneumocystis carinii pneumonia associated with adrenocorticotropic hormone treatment for infantile spasms.
European journal of pediatrics 1992 Nov;151;867 1992 Nov
[Fatal Pneumocystis carinii pneumonia during ACTH therapy of West syndrome].
Anales espanoles de pediatria 1990 May;32;457-9 1990 May
Pneumocystis carinii pneumonia in infants given adrenocorticotropic hormone for infantile spasms.
The Journal of pediatrics 1987 Jun;110;901-3 1987 Jun

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