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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Gemcitabine

5

I.ad Radiation recall pneumonitis

1
Last update : 27/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary Radiation Recall Induced by Gemcitabine.
American journal of respiratory and critical care medicine 2016 Oct 01;194;909-910 2016 Oct 01
High frequency of radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent radiotherapy and gemcitabine after induction with gemcitabine and carboplatin.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009 Jul;4;845-52 2009 Jul
Radiation recall pneumonitis induced by gemcitabine.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 2007 Apr;183;215-7 2007 Apr
Gemcitabine-induced radiation recall.
International journal of radiation oncology, biology, physics 2002 Jun 01;53;394-400 2002 Jun 01
Radiation recall reaction following gemcitabine.
Lung cancer (Amsterdam, Netherlands) 2001;33;299-302 2001
Side effects of chemotherapy. Case 2. Radiation recall reaction induced by gemcitabine.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000 Feb;18;695-6 2000 Feb

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