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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Gemcitabine

5

IV.b Bronchospasm and angioedema

1
Last update : 17/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Gemcitabine-induced erysipeloid skin lesions in a patient with malignant mesothelioma.
Journal of the European Academy of Dermatology and Venereology : JEADV 2002 May;16;271-2 2002 May
Phase II study of gemcitabine and vindesine in patients with previously untreated non-resectable non-small-cell lung cancer.
British journal of cancer 1999 Feb;79;875-81 1999 Feb

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