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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxymorphone

2

X.af Thrombotic microangiopathy

2
Last update : 12/01/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

After the Party's Over.
The New England journal of medicine 2017 Jan 05;376;74-80 2017 Jan 05
Thrombotic thrombocytopenic purpura (TTP)-like illness associated with intravenous Opana ER abuse--Tennessee, 2012.
MMWR. Morbidity and mortality weekly report 2013 Jan 11;62;1-4 2013 Jan 11

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