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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Colistin, inhaled

3

IV.a Bronchospasm - Wheezing - Asthma

2
Last update : 02/01/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Colistin-Colimycin
2

Publications

Evaluation of bronchial constriction in children with cystic fibrosis after inhaling two different preparations of tobramycin.
Chest 2002 Sep;122;930-4 2002 Sep

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