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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Trifluridine-tipiracil (TAS-102)

1

I.b Pneumonitis (ILD)

1
Last update : 07/11/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[A Case of Interstitial Pneumonitis Induced by TAS-102 for Liver and Lung Metastasis of Colorectal Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2018 Sep;45;1365-1368 2018 Sep
Interstitial pneumonia in a patient treated with TAS-102 for metastatic colorectal cancer: a case report.
Journal of medical case reports 2016 Nov 03;10;310 2016 Nov 03

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