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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fluticasone (inhaled - ICS)

4

XVII.a Respiratory tract infection incl. pneumonia

3
Last update : 18/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Corticosteroids, inhaled (ICS)
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Publications

Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD.
The New England journal of medicine 2018 May 03;378;1671-1680 2018 May 03
Scientific rationale for the possible inhaled corticosteroid intraclass difference in the risk of pneumonia in COPD.
International journal of chronic obstructive pulmonary disease 2017;12;3055-3064 2017
Pneumonia risk with inhaled fluticasone furoate and vilanterol compared with vilanterol alone in patients with COPD.
Annals of the American Thoracic Society 2015 Jan;12;27-34 2015 Jan
Meta-review: adverse effects of inhaled corticosteroids relevant to older patients.
Drugs 2014 Apr;74;539-47 2014 Apr
Inhaled corticosteroids in COPD and the risk of serious pneumonia.
Thorax 2013 Nov;68;1029-36 2013 Nov

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