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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carboxymethylcellulose (topical)

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 10/10/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Excipients-Vehicle-Preservatives (of drugs)
5

Publications

Anaphylaxis from the carboxymethylcellulose component of barium sulfate suspension.
The New England journal of medicine 1998 Feb 26;338;623 1998 Feb 26
Anaphylaxis induced by the carboxymethylcellulose component of injectable triamcinolone acetonide suspension (Kenalog).
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1995 Feb;74;163-6 1995 Feb

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