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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Benralizumab

1

XVII.a Respiratory tract infection incl. pneumonia

1
Last update : 01/03/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.
The Lancet. Respiratory medicine 2014 Nov;2;879-890 2014 Nov

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