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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Regorafenib

1

XVI.bf Imaging: Tumoral cavitation

1
Last update : 13/02/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[A Patient with Cavitated Pulmonary Metastases Treated with Regorafenib].
Gan to kagaku ryoho. Cancer & chemotherapy 2016 Jun;43;757-9 2016 Jun
Early tumor cavitation with regorafenib in metastatic colorectal cancer: A case report.
Oncology letters 2016 Jan;11;231-233 2016 Jan
Bilateral spontaneous pneumothorax and massive pneumomediastinum under Pazopanib therapy.
Thoracic cancer 2015 Jan;6;110-1 2015 Jan

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