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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraffin (aspirated)

5

I.g Pulmonary fibrosis

2
Last update : 23/04/2023
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Laxatives - Cathartics
1
Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated
5

Publications

The spectrum of lung disease due to chronic occult aspiration.
Annals of the American Thoracic Society 2014 Jul;11;865-73 2014 Jul

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