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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Flecainide

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 05/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Flecaine
2

Publications

Flecainide-induced pneumonitis: a case report.
Journal of medical case reports 2022 Nov 02;16;404 2022 Nov 02
Drug-induced acute pneumonitis following initiation of flecainide therapy after pulmonary vein isolation ablation in a patient with mitral stenosis and previous chronic amiodarone use.
HeartRhythm case reports 2019 Jan;5;53-55 2019 Jan
Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome.
Acta cardiologica 2000 Feb;55;45-7 2000 Feb
Flecainide-associated interstitial pneumonitis.
Lancet (London, England) 1991 Feb 09;337;371-2 1991 Feb 09

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