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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cisplatin (endobronchial/intratumoral)

1

VIII.ab Airway (e.g. tracheoesophageal) fistula

1
Last update : 06/11/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Treatment of isolated mediastinal and hilar recurrence of lung cancer with bronchoscopic endobronchial ultrasound guided intratumoral injection of chemotherapy with cisplatin.
Lung cancer (Amsterdam, Netherlands) 2015 Dec;90;542-7 2015 Dec

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