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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Pulmonary vasodilator therapy

3

II.d Pulmonary edema, cardiogenic

1
Last update : 03/10/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Epoprostenol
3
Macitentan
1
Prostacyclin
3
Prostaglandin E1
1
Prostaglandin F2-alpha
1
Prostaglandins
1
Pulmonary hypertension therapy
2

Publications

Severely worsening dyspnea after initiation of macitentan therapy for pulmonary arterial hypertension.
International journal of cardiology 2016 Jan 01;202;244-5 2016 Jan 01

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