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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fentanyl

5

IX.c Chest wall muscle rigidity - Stiff/wooden chest

1
Last update : 06/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Acetylfentanyl
1
Butyrfentanyl
2
Carfentanyl (carboxymethoxyfentanyl)
2
Fentanyl (smoked, snorted, insufflated, inhaled)
2
Fentanyl (topical)
3
Fentanyl analogs/derivatives/substituted
5
Opiates - Opioids - Opium
5

Publications

Fentanyl-Induced Rigid Chest Syndrome in Critically Ill Patients.
Journal of intensive care medicine 2023 Feb;38;196-201 2023 Feb
Case Report of Very-Low-Dose Fentanyl Causing Fentanyl-Induced Chest Wall Rigidity.
Cureus 2023 Aug;15;e43788 2023 Aug
Wooden Chest Syndrome: A Case Report of Fentanyl-Induced Chest Wall Rigidity.
Journal of investigative medicine high impact case reports 2021;9;23247096211034036 2021
Novel Synthetic Opioids: The Pathologist's Point of View.
Brain sciences 2018 Sep 02;8; 2018 Sep 02
Fentanyl-induced chest wall rigidity syndrome in a routine bronchoscopy.
Respiratory medicine case reports 2017;20;205-207 2017
Fentanyl-induced chest wall rigidity.
Chest 2013 Apr;143;1145-1146 2013 Apr
Case of chest-wall rigidity in a preterm infant caused by prenatal fentanyl administration.
Journal of perinatology : official journal of the California Perinatal Association 2010 Feb;30;149-50 2010 Feb
Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants.
Critical care medicine 2000 Mar;28;836-9 2000 Mar
Three cases with different presentation of fentanyl-induced muscle rigidity--a rare problem in intensive care of neonates.
American journal of perinatology 2000;17;23-6 2000

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