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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fentanyl

5

XI.r Death following exposure or poisoning

3
Last update : 26/04/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Acetylfentanyl
1
Butyrfentanyl
2
Carfentanyl (carboxymethoxyfentanyl)
2
Fentanyl (smoked, snorted, insufflated, inhaled)
2
Fentanyl (topical)
3
Fentanyl analogs/derivatives/substituted
5
Opiates - Opioids - Opium
5

Publications

Fatal Transdermal Fentanyl Patch Overdose in a Child.
Cureus 2020 Jan 23;12;e6755 2020 Jan 23
Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis.
The Journal of pharmacology and experimental therapeutics 2019 Nov;371;453-475 2019 Nov
Fatal Fentanyl: One Pill Can Kill.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2017 Jan;24;106-113 2017 Jan
Multiple Fentanyl Overdoses - New Haven, Connecticut, June 23, 2016.
MMWR. Morbidity and mortality weekly report 2017 Feb 03;66;107-111 2017 Feb 03
Assisted suicide by fentanyl intoxication due to excessive transdermal application.
International journal of legal medicine 2014 Nov;128;949-56 2014 Nov
Deaths with transdermal fentanyl patches.
The American journal of forensic medicine and pathology 2010 Mar;31;18-21 2010 Mar
Transdermal fentanyl: pharmacology and toxicology.
Journal of medical toxicology : official journal of the American College of Medical Toxicology 2009 Dec;5;230-41 2009 Dec
Fentanyl use, misuse, and abuse: a summary of 23 postmortem cases.
Journal of analytical toxicology 2003 Oct;27;499-504 2003 Oct
Fentanyl-related deaths: demographics, circumstances, and toxicology of 112 cases.
Journal of forensic sciences 1991 Mar;36;422-33 1991 Mar

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