Pneumotox » Drug » BCG vaccination » XVII.i - Mycobacterium bovis/BCG infection

BCG vaccination

Risk increases in naturally or iatrogenically immunosuppressed individuals (PMID 12856232). Can be fatal

Last update : 22/04/2019

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment