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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vedolizumab

2

XVI.v Imaging: Centrilobular micronodules (can be diffuse)

1
Last update : 14/08/2022
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Vedolizumab-induced acute interstitial lung injury in a 39-year-old male with ulcerative colitis.
European journal of gastroenterology & hepatology 2021 Dec 01;33;e1057-e1059 2021 Dec 01

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