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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Poison hemlock
1
IX.a
Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)
1
From
Conium maculatum
Last update :
18/04/2015
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Herbals - Dietary botanical therapy - Health products/food - Plants
Publications
Conium maculatum intoxication: Literature review and case report on hemlock poisoning.
Prolonged ventilatory failure and flaccid quadriparesis after ingestion of poison hemlock.