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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Acetylcholine

1

XII.g Coronary artery disease (acute) - Myocardial ischemia/infarction

1
Last update : 17/03/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Serious cardiac complications in coronary spasm provocation tests using acetylcholine or ergonovine: analysis of 21 512 patients from the diagnosis procedure combination database in Japan.
Clinical cardiology 2015 Mar;38;171-7 2015 Mar

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