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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Organic dust

5

XV.a Path: NSIP-cellular pattern (see also Ia, Ib)

5
Last update : 06/03/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Pituitary snuff
1

Publications

Hypersensitivity pneumonitis: a review and update of histologic findings.
Journal of clinical pathology 2013 Oct;66;888-95 2013 Oct
Hypersensitivity pneumonia: the role of lung biopsy in diagnosis and management.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012 Jan;25 Suppl 1;S58-67 2012 Jan
Hypersensitivity pneumonitis: histopathology.
Archives of pathology & laboratory medicine 2008 Feb;132;199-203 2008 Feb

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